| Motor | Motorkod | Bränsle | Original (hk) |
|---|---|---|---|
| 350d 286hp | OM656 DE 30 LA | diesel | 286 |
| 400d 340hp | OM656.929 | diesel | 340 |
| 450 - 367hp | M256.930 | diesel | 367 |
| 500 Plug-in Hybrid - 442hp | M276 | bensin | 442 |
| 560 - 469hp | M176.980 | bensin | 469 |
| 63 AMG S 612hp | M177.980 | bensin | 612 |
| 65 AMG 630hp | M277.980, M 279.870 | bensin | 630 |
| 650 - 630hp | M 279.870 | bensin | 630 |
Motoroptimering Mercedes-Benz S W222 2017–2019